Is Obesity Related to Gut Microbes?
Monday, October 22nd, 2007Gut microbes may represent valuable clues to determine the cause and treatment of obesity. Trillions of gut microbes break down complex molecules into simple sugars for energy and the excess is transformed into fat for long term storage.
This is the subject of a study conducted at Washington University School of Medicine, which shows that the balance between the two major families of intestinal bacteria changes when obese people lose weight.
The firmicutes and bacteriodetes represent almost ninety percent of the microbes in the gut of humans and white mice. They are considered to influence the weight loss.
Researchers found that when a person loses weight the number of bacteroidetes increases. A study on white mice proved that in case of the obese mice the gut bacteria has less bacteroidetes, and the same thing seems to happen to obese humans but the effects are different from one person to another.
Bacteria in the gut of obese mice could extract calories from complex carbohydrates easier than bacteria in the gut of slim mice, showed the study.
Gut microbes are considered by researchers to be biomarkers, mediators and potential therapeutic targets when it comes to fighting against obesity.